PLCG2 (phospho Y1217) polyclonal antibody
产品名称： PLCG2 (phospho Y1217) polyclonal antibody
英文名称： PLCG2 (phospho Y1217) polyclonal antibody
产品编号： PAB7766
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of PLCG2.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding Y1217 of human PLCG2.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 150
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 5336
- Protein Accession#:
- P16885
- Gene Name:
- PLCG2
- Gene Alias:
- -
- Gene Description:
- phospholipase C, gamma 2 (phosphatidylinositol-specific)
- Omim ID:
- 600220
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C-beta is regulated by heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1; MIM 172420) and C-gamma-2 enzymes are controlled by receptor tyrosine kinases. The C-gamma-1 and C-gamma-2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.[supplied by OMIM
- Other Designations:
- phospholipase C gamma 2,phospholipase C, gamma 2,phospholipase C, gamma 2 (phosphatidylyinositol-specific)
- Gene Pathway
- B cell receptor signaling pathway
- Calcium signaling pathway
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Glioma
- Inositol phosphate metabolism
- Leukocyte transendothelial migration
- Metabolic pathways
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pathways in cancer
- Phosphatidylinositol signaling system
- VEGF signaling pathway
- Vibrio cholerae infection